Xavi believes forcing Barcelona to play Real Mallorca on Sunday is "crazy" due to the Blaugrana's 17 first-team absences.
Barca were hit with a spate of Covid-19 cases during the winter break, with as many as 10 players testing positive for the illness.
One of those – Samuel Umtiti – has since returned a negative test meaning he is technically available for Sunday's trip, though he is not deemed match fit after being unable to train in the past week.
Additionally, Xavi is without five players through injury; Sergio Busquets is suspended; Yusuf Demir is negotiating his departure; and Ferran Torres, who is injured anyway, cannot be registered until Monday at the earliest.
While postponements have become commonplace in other competitions, such as the Premier League, regulations in La Liga make such situations much rarer.
Teams will still have to play so long as they have 13 available players from their first and second teams. Clubs must continue to adhere to the rule that dictates a minimum of seven players registered to the senior team are on the pitch at the same time.
But that minimum can drop to five players if teams have fewer than seven professionals available for selection – essentially, as long as Barca can name five first-team players in a starting team, their games will not be postponed, much to the frustration of Xavi.
"It makes no sense to play tomorrow," Xavi told reporters in Saturday's pre-match news conference.
"We are in an extreme situation. We have between 17-18 casualties, it depends on Umtiti, who today has tested negative but has not trained for a week.
Suspend the game
"It's a time to suspend the game. In this way [not postponing the game], the competition is adulterated, it is crazy to play like this.
"We have no choice but to compete with who we have. Mallorca has also asked for it [the game to be postponed].
"We must appeal to common sense. It's not a complaint, it's a reality. Basketball has been suspended.
"We will play if La Liga forces us. We've trained well, but it's a chaotic situation. Be that as it may, we will go out to compete and try to win."
Barca head into their first game of 2022 seventh in La Liga, 18 points adrift of leaders Real Madrid.